MHC Class I Antibodies

Target Information

Like their mammalian counterparts, avian MHC Class I molecules, also known as B-F antigens, consist of a highly polymorphic alpha-chain noncovalently bound to the invariant beta2-microglobulin subunit. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. The monoclonal antibody F21-2 also reacts with turkey MHC Class I. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Synonyms

A29 protein; antigen presenting molecule; Aw-33; Aw-74; B12; BF; B-F; B-F histocompatibility F10 antigen; B-F major; B-F minor; BF1; BF12; BF2; BFa1; BFa2; B-F-beta-IV; B-FI; BFIV; B-FIV; BFIV21; B-F-S01; B-F-S02; B-F-S03; B-F-S04; B-F-S05; B-F-S06; B-F-S07; B-F-S09; B-F-S11; B-F-S12; B-F-S13; B-F-S14; BFw-03; BFw-05; BFz-01; B-LB2; BOLA class I histocompatibility antigen, alpha chain BL3-7-like; class I histocompatibility antigen, F10 alpha chain; F10 alpha chain; HLA A; HLA class I antigen; HLA class I histocompatibility antigen, A alpha chain; HLA class I histocompatibility antigen, A-1 alpha chain; HLA class I histocompatibility antigen, A-30 alpha chain; HLA class I histocompatibility antigen, A-33 alpha chain; HLA class I histocompatibility antigen, A-74 alpha chain; HLA locus; HLAA; HLA-A; HLA-A locus alpha 2 domain; HLA-A null; HLA-A11; HLA-A33; HLA-Aw33.1; HLA-DQB1; HLA-DRB1; Human leukocyte antigen A; leukocyte antigen class I-A; Major histocompatibility complex class I antigen BF2; major histocompatibility complex class I glycoprotein; major histocompatibility complex, class I, A; major histocompatibility complex, class I, G; MCH class I antigen; MHC BF1 class I; MHC BF2 class I; MHC class 1 antigen; MHC class I alpha chain 1; MHC class I alpha chain 2; MHC class I anti; MHC class I antigen; MHC class I antigen A*30; MHC class I antigen A*33; MHC class I antigen A*74; MHC class I antigen alpha chain; MHC class I antigen B-F heavy chain; MHC class I antigen B-F major heavy chain; MHC class I antigen heavy chain; MHC class I antigen HLA-A heavy chain; MHC class I antigen HLA-A33; MHC class I antigen null protein; MHC class I antigene; MHC class I glycoprotein; MHC class I molecule; MHC class II antigen; MHC classI antigen; OLA-I; OVAR; Ovar-I; ovar-MHCI-B564; ovar-MHCI-D5; ovar-MHCI-F12; truncated MHC class I antigen